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Specific and Aspecific Molecular Checkpoints as Potential Targets for Dismantling Tumor Hierarchy and Preventing Relapse and Metastasis Through Shielded Cytolytic Treatments

I have recently theorized that several similarities exist between the tumor process and embryo development. Starting from an initial cancer stem cell (CSC(0)), similar to an embryonic stem cell (ESC), after implantation in a niche, primary self-renewing CSCs (CSC(1)s) would arise, which then generat...

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Detalles Bibliográficos
Autor principal: Manzo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291084/
https://www.ncbi.nlm.nih.gov/pubmed/34295890
http://dx.doi.org/10.3389/fcell.2021.665321