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PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s Disease

Parkinson’s disease (PD) is an age-related neurodegenerative disorder affecting millions of people worldwide. The disease is characterized by the progressive loss of dopaminergic neurons and spread of Lewy pathology (α-synuclein aggregates) in the brain but the pathogenesis remains elusive. PD prese...

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Detalles Bibliográficos
Autores principales: Li, Wen, Fu, YuHong, Halliday, Glenda M., Sue, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291125/
https://www.ncbi.nlm.nih.gov/pubmed/34295884
http://dx.doi.org/10.3389/fcell.2021.612476