Cargando…
GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury
RATIONALE: Pyroptosis is a morphologically and mechanistically distinct form of cell death and is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis with excessive inflammatory factor release. Cardiomyocyte necrosis and inflammation play key roles in the pathophysiology of...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291144/ https://www.ncbi.nlm.nih.gov/pubmed/34015941 http://dx.doi.org/10.1161/CIRCRESAHA.120.318629 |