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GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury

RATIONALE: Pyroptosis is a morphologically and mechanistically distinct form of cell death and is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis with excessive inflammatory factor release. Cardiomyocyte necrosis and inflammation play key roles in the pathophysiology of...

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Detalles Bibliográficos
Autores principales:	Shi, Huairui, Gao, Yang, Dong, Zhen, Yang, Ji’e, Gao, Rifeng, Li, Xiao, Zhang, Shuqi, Ma, Leilei, Sun, Xiaolei, Wang, Zeng, Zhang, Feng, Hu, Kai, Sun, Aijun, Ge, Junbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291144/ https://www.ncbi.nlm.nih.gov/pubmed/34015941 http://dx.doi.org/10.1161/CIRCRESAHA.120.318629

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