Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

Type 2 diabetes (T2D) is a well-known risk factor for tuberculosis (TB), but little is known about pre-diabetes and the relative contribution of impaired glucose tolerance vs. obesity towards susceptibility to TB. Here, we developed a preclinical model of pre-diabetes and TB. Mice fed a high fat die...

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Detalles Bibliográficos
Autores principales: Sinha, Roma, Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Keshvari, Sahar, Hasnain, Sumaira Z., Donovan, Meg L., Kling, Jessica C., Blumenthal, Antje, Chen, Chen, Short, Kirsty R., Ronacher, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291147/
https://www.ncbi.nlm.nih.gov/pubmed/34295838
http://dx.doi.org/10.3389/fcimb.2021.691823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291147/
https://www.ncbi.nlm.nih.gov/pubmed/34295838
http://dx.doi.org/10.3389/fcimb.2021.691823

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