DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

BACKGROUND: Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking. METHODS: A novel approach of reference-free deconvolution of large-scale DNA methylation data en...

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Detalles Bibliográficos
Autores principales: Filipski, Katharina, Scherer, Michael, Zeiner, Kim N., Bucher, Andreas, Kleemann, Johannes, Jurmeister, Philipp, Hartung, Tabea I., Meissner, Markus, Plate, Karl H., Fenton, Tim R., Walter, Jörn, Tierling, Sascha, Schilling, Bastian, Zeiner, Pia S., Harter, Patrick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291310/
https://www.ncbi.nlm.nih.gov/pubmed/34281986
http://dx.doi.org/10.1136/jitc-2020-002226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291310/
https://www.ncbi.nlm.nih.gov/pubmed/34281986
http://dx.doi.org/10.1136/jitc-2020-002226

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