How mouse RAG recombinase avoids DNA transposition

The RAG1-RAG2 recombinase (RAG) cleaves DNA to initiate V(D)J recombination. But RAG also belongs to the RNH-type transposase family. To learn how RAG-catalyzed transposition is inhibited in developing lymphocytes, we determined the structure of a DNA strand-transfer complex of mouse RAG at 3.1 Å re...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xuemin, Cui, Yanxiang, Wang, Huaibin, Zhou, Z. Hong, Gellert, Martin, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291384/
https://www.ncbi.nlm.nih.gov/pubmed/32015553
http://dx.doi.org/10.1038/s41594-019-0366-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291384/
https://www.ncbi.nlm.nih.gov/pubmed/32015553
http://dx.doi.org/10.1038/s41594-019-0366-z

Ejemplares similares