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Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders

Human genetic adaptation to high altitudes (>2500 m) has been extensively studied over the last few years, but few functional adaptive genetic variants have been identified, largely owing to the lack of deep-genome sequencing data available to previous studies. Here, we build a list of putative a...

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Detalles Bibliográficos
Autores principales: Deng, Lian, Zhang, Chao, Yuan, Kai, Gao, Yang, Pan, Yuwen, Ge, Xueling, He, Yaoxi, Yuan, Yuan, Lu, Yan, Zhang, Xiaoxi, Chen, Hao, Lou, Haiyi, Wang, Xiaoji, Lu, Dongsheng, Liu, Jiaojiao, Tian, Lei, Feng, Qidi, Khan, Asifullah, Yang, Yajun, Jin, Zi-Bing, Yang, Jian, Lu, Fan, Qu, Jia, Kang, Longli, Su, Bing, Xu, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291452/
https://www.ncbi.nlm.nih.gov/pubmed/34691999
http://dx.doi.org/10.1093/nsr/nwz108