Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain

[Image: see text] Detailed metabolic imaging of specific brain regions in early aging may expose pathophysiological mechanisms and indicate effective neuropharmacological targets in the onset of cognitive decline. Comprehensive imaging of brain aging and drug-target effects is restricted using conve...

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Detalles Bibliográficos
Autores principales: Vallianatou, Theodosia, Shariatgorji, Reza, Nilsson, Anna, Karlgren, Maria, Hulme, Heather, Fridjonsdottir, Elva, Svenningsson, Per, Andrén, Per E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291481/
https://www.ncbi.nlm.nih.gov/pubmed/33939923
http://dx.doi.org/10.1021/acschemneuro.1c00103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291481/
https://www.ncbi.nlm.nih.gov/pubmed/33939923
http://dx.doi.org/10.1021/acschemneuro.1c00103

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