Dual Inhibitors of Amyloid-β and Tau Aggregation with Amyloid-β Disaggregating Properties: Extended In Cellulo, In Silico, and Kinetic Studies of Multifunctional Anti-Alzheimer’s Agents

[Image: see text] In Alzheimer’s disease, neurons slowly degenerate due to the accumulation of misfolded amyloid β and tau proteins. In our research, we performed extended studies directed at amyloid β and tau aggregation inhibition using in cellulo (Escherichia coli model of protein aggregation), i...

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Detalles Bibliográficos
Autores principales: Pasieka, Anna, Panek, Dawid, Szałaj, Natalia, Espargaró, Alba, Więckowska, Anna, Malawska, Barbara, Sabaté, Raimon, Bajda, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291496/
https://www.ncbi.nlm.nih.gov/pubmed/34019757
http://dx.doi.org/10.1021/acschemneuro.1c00235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291496/
https://www.ncbi.nlm.nih.gov/pubmed/34019757
http://dx.doi.org/10.1021/acschemneuro.1c00235

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