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Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain
[Image: see text] Intrinsically disordered regions in proteins often function as binding motifs in protein–protein interactions. The mechanistic aspects and molecular details of such coupled binding and folding reactions, which involve formation of multiple noncovalent bonds, have been broadly studi...
Autores principales: | Jensen, Thomas M. T., Bartling, Christian R. O., Karlsson, O. Andreas, Åberg, Emma, Haugaard-Kedström, Linda M., Strømgaard, Kristian, Jemth, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291497/ https://www.ncbi.nlm.nih.gov/pubmed/34161732 http://dx.doi.org/10.1021/acschembio.1c00176 |
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