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Domain-Independent Inhibition of CBP/p300 Attenuates α-Synuclein Aggregation

[Image: see text] Neurodegenerative diseases are associated with failed proteostasis and accumulation of insoluble protein aggregates that compromise neuronal function and survival. In Parkinson’s disease, a major pathological finding is Lewy bodies and neurites that are mainly composed of phosphory...

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Detalles Bibliográficos
Autores principales: Hlushchuk, Irena, Ruskoaho, Heikki, Domanskyi, Andrii, Airavaara, Mikko, Välimäki, Mika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291498/
https://www.ncbi.nlm.nih.gov/pubmed/34110772
http://dx.doi.org/10.1021/acschemneuro.1c00215