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Domain-Independent Inhibition of CBP/p300 Attenuates α-Synuclein Aggregation
[Image: see text] Neurodegenerative diseases are associated with failed proteostasis and accumulation of insoluble protein aggregates that compromise neuronal function and survival. In Parkinson’s disease, a major pathological finding is Lewy bodies and neurites that are mainly composed of phosphory...
Autores principales: | Hlushchuk, Irena, Ruskoaho, Heikki, Domanskyi, Andrii, Airavaara, Mikko, Välimäki, Mika J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291498/ https://www.ncbi.nlm.nih.gov/pubmed/34110772 http://dx.doi.org/10.1021/acschemneuro.1c00215 |
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