Detection for disease tipping points by landscape dynamic network biomarkers

A new model-free method has been developed and termed the landscape dynamic network biomarker (l-DNB) methodology. The method is based on bifurcation theory, which can identify tipping points prior to serious disease deterioration using only single-sample omics data. Here, we show that l-DNB provide...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoping, Chang, Xiao, Leng, Siyang, Tang, Hui, Aihara, Kazuyuki, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291500/
https://www.ncbi.nlm.nih.gov/pubmed/34691933
http://dx.doi.org/10.1093/nsr/nwy162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291500/
https://www.ncbi.nlm.nih.gov/pubmed/34691933
http://dx.doi.org/10.1093/nsr/nwy162

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