General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams

[Image: see text] An iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidine synthesis via [3 + 2] dipolar cycloaddition reactions is described. Proceeding under mild reaction conditions from both amide and lact...

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Detalles Bibliográficos
Autores principales: Yamazaki, Ken, Gabriel, Pablo, Di Carmine, Graziano, Pedroni, Julia, Farizyan, Mirxan, Hamlin, Trevor A., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291578/
https://www.ncbi.nlm.nih.gov/pubmed/34306810
http://dx.doi.org/10.1021/acscatal.1c01589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291578/
https://www.ncbi.nlm.nih.gov/pubmed/34306810
http://dx.doi.org/10.1021/acscatal.1c01589

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