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Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer’s Disease Following Treatment with a Brain-Targeting Somatostatin Peptide

[Image: see text] Alzheimer’s disease is the most common neurodegenerative disorder characterized by the pathological aggregation of amyloid-β (Aβ) peptide. A potential therapeutic intervention in Alzheimer’s disease is to enhance Aβ degradation by increasing the activity of Aβ-degrading enzymes, in...

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Detalles Bibliográficos
Autores principales: Rofo, Fadi, Sandbaumhüter, Friederike A., Chourlia, Aikaterini, Metzendorf, Nicole G., Morrison, Jamie I., Syvänen, Stina, Andrén, Per E., Jansson, Erik T., Hultqvist, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291608/
https://www.ncbi.nlm.nih.gov/pubmed/34170117
http://dx.doi.org/10.1021/acschemneuro.1c00303