The multi-functional reovirus σ3 protein is a virulence factor that suppresses stress granule formation and is associated with myocardial injury

The mammalian orthoreovirus double-stranded (ds) RNA-binding protein σ3 is a multifunctional protein that promotes viral protein synthesis and facilitates viral entry and assembly. The dsRNA-binding capacity of σ3 correlates with its capacity to prevent dsRNA-mediated activation of protein kinase R...

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Detalles Bibliográficos
Autores principales: Guo, Yingying, Hinchman, Meleana M., Lewandrowski, Mercedes, Cross, Shaun T., Sutherland, Danica M., Welsh, Olivia L., Dermody, Terence S., Parker, John S. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291629/
https://www.ncbi.nlm.nih.gov/pubmed/34237110
http://dx.doi.org/10.1371/journal.ppat.1009494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291629/
https://www.ncbi.nlm.nih.gov/pubmed/34237110
http://dx.doi.org/10.1371/journal.ppat.1009494

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