BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the western world. In previous studies, various proportion of patients was found to carry CD11b(+) or CD11c(+) B cells whose presence was an unfavourable prognostic factor. The exact mechanism however, how these receptors contribute...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagy-Baló, Zsuzsa, Kiss, Richárd, Demeter, Judit, Bödör, Csaba, Bajtay, Zsuzsa, Erdei, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291664/
https://www.ncbi.nlm.nih.gov/pubmed/34283878
http://dx.doi.org/10.1371/journal.pone.0254853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291664/
https://www.ncbi.nlm.nih.gov/pubmed/34283878
http://dx.doi.org/10.1371/journal.pone.0254853

Ejemplares similares