Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans

The intracellular level of fatty aldehydes is tightly regulated by aldehyde dehydrogenases to minimize the formation of toxic lipid and protein adducts. Importantly, the dysregulation of aldehyde dehydrogenases has been implicated in neurologic disorder and cancer in humans. However, cellular respon...

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Detalles Bibliográficos
Autores principales: Zeng, Lidan, Li, Xuesong, Preusch, Christopher B., He, Gary J., Xu, Ningyi, Cheung, Tom H., Qu, Jianan, Mak, Ho Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291716/
https://www.ncbi.nlm.nih.gov/pubmed/34237064
http://dx.doi.org/10.1371/journal.pgen.1009635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291716/
https://www.ncbi.nlm.nih.gov/pubmed/34237064
http://dx.doi.org/10.1371/journal.pgen.1009635

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