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Prolonged use of letrozole causes morphological changes on gonads in Galea spixii

Letrozole is used as a therapeutic agent in reproductive disorders caused by high estrogen levels. Letrozole inhibits cytochrome P450 aromatase and reduces estrogen levels. However, the effects of long-term use on reproductive traits are unknown. The aim of this study was to evaluate the prolonged u...

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Detalles Bibliográficos
Autores principales: Arroyo, Maria Angelica Machado, Santos, Paulo Ramos da Silva, de Oliveira, Moacir Franco, de Assis, Antônio Chaves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Reprodução Animal 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291776/
https://www.ncbi.nlm.nih.gov/pubmed/34306212
http://dx.doi.org/10.1590/1984-3143-AR2020-0029