Silencing cyclophilin A improves insulin secretion, reduces cell apoptosis, and alleviates inflammation as well as oxidant stress in high glucose-induced pancreatic β-cells via MAPK/NF-kb signaling pathway

Cyclophilin A is increased in the plasm of diabetic patients, while its effects on high glucose (HG)-stimulated pancreatic β-cells are still pending. The aim of this research is to investigate the effects of cyclophilin A inhibition on HG-challenged pancreatic β-cells. For investigating the effects...

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Detalles Bibliográficos
Autores principales: Li, Tangying, Quan, Huibiao, Zhang, Huachuan, Lin, Leweihua, Ou, Qianying, Chen, Kaining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291783/
https://www.ncbi.nlm.nih.gov/pubmed/32970961
http://dx.doi.org/10.1080/21655979.2020.1823729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291783/
https://www.ncbi.nlm.nih.gov/pubmed/32970961
http://dx.doi.org/10.1080/21655979.2020.1823729

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