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Platelet-concentrated and platelet poor-plasma promote different pattern on immunohistochemical expression of TGF-β1, however they impairs the osteoneogensis in calvarial defects treated with autograft due suppression of osteocalcin

PURPOSE: Herein we evaluated the effects of platelet concentrate (PC) and platelet-poor plasma (PPP) on bone repair using noncritical defects in the calvaria of rabbits and compared them to the presence of TGF-β1 and osteocalcin on reparative sites. METHODS: Five noncritical defects of 8.7 mm in dia...

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Detalles Bibliográficos
Autores principales: de Oliveira-Filho, Marco Antonio, Souza, Marcelo, Tabushi, Fernando Issamu, Almeida, Luís Eduardo, Figueiredo, Fernanda Pirajá, Lourenço, Elora Sampaio, Giovanini, Allan Fernando, Malafaia, Osvaldo, Ribas, Jurandir Marcondes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291903/
https://www.ncbi.nlm.nih.gov/pubmed/34287607
http://dx.doi.org/10.1590/ACB360604