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How the vacuole ESCRTs its own proteins to their final destination

Lysosomes (vacuoles in yeast) are master regulators of metabolism and protein turnover, but how they degrade their own resident proteins is unclear. Recently, multiple models have been proposed explaining yeast vacuole protein sorting, but the role of the ESCRT pathway was unclear. In this JCB issue...

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Detalles Bibliográficos
Autor principal: Henne, W. Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292134/
https://www.ncbi.nlm.nih.gov/pubmed/34279549
http://dx.doi.org/10.1083/jcb.202105177