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GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer’s disease

In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic) system in age-related episodic memory impairments in humans, with a particular focus on Alzheimer’s disease (AD). Well-established animal models have shown that GABA plays a central role in regulating and sync...

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Detalles Bibliográficos
Autores principales: Jiménez-Balado, Joan, Eich, Teal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292162/
https://www.ncbi.nlm.nih.gov/pubmed/33573856
http://dx.doi.org/10.1016/j.semcdb.2021.01.005