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The thrombopoietin receptor: revisiting the master regulator of platelet production

Thrombopoietin (TPO) and its receptor, MPL, are the primary regulators of platelet production and critical for hematopoietic stem cell (HSC) maintenance. Since TPO was first cloned in 1994, the physiological and pathological roles of TPO and MPL have been well characterized, culminating in the first...

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Detalles Bibliográficos
Autores principales: Hitchcock, Ian S., Hafer, Maximillian, Sangkhae, Veena, Tucker, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292222/
https://www.ncbi.nlm.nih.gov/pubmed/34097561
http://dx.doi.org/10.1080/09537104.2021.1925102