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Nalmefene attenuates neural alcohol cue-reactivity in the ventral striatum and subjective alcohol craving in patients with alcohol use disorder

RATIONALE: Alcohol use disorder is a common and devastating mental illness for which satisfactory treatments are still lacking. Nalmefene, as an opioid receptor modulator, could pharmacologically support the reduction of drinking by reducing the (anticipated) rewarding effects of alcohol and expandi...

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Detalles Bibliográficos
Autores principales: Karl, Damian, Bumb, J. Malte, Bach, Patrick, Dinter, Christina, Koopmann, Anne, Hermann, Derik, Mann, Karl, Kiefer, Falk, Vollstädt-Klein, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292278/
https://www.ncbi.nlm.nih.gov/pubmed/33846866
http://dx.doi.org/10.1007/s00213-021-05842-7