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TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

Activation of fibroblasts is essential for physiological tissue repair. Uncontrolled activation of fibroblasts, however, may lead to tissue fibrosis with organ dysfunction. Although several pathways capable of promoting fibroblast activation and tissue repair have been identified, their interplay in...

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Detalles Bibliográficos
Autores principales: Zehender, Ariella, Li, Yi-Nan, Lin, Neng-Yu, Stefanica, Adrian, Nüchel, Julian, Chen, Chih-Wei, Hsu, Hsiao-Han, Zhu, Honglin, Ding, Xiao, Huang, Jingang, Shen, Lichong, Györfi, Andrea-Hermina, Soare, Alina, Rauber, Simon, Bergmann, Christina, Ramming, Andreas, Plomann, Markus, Eckes, Beate, Schett, Georg, Distler, Jörg H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292318/
https://www.ncbi.nlm.nih.gov/pubmed/34285225
http://dx.doi.org/10.1038/s41467-021-24601-y