Cargando…
TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy
Activation of fibroblasts is essential for physiological tissue repair. Uncontrolled activation of fibroblasts, however, may lead to tissue fibrosis with organ dysfunction. Although several pathways capable of promoting fibroblast activation and tissue repair have been identified, their interplay in...
Autores principales: | Zehender, Ariella, Li, Yi-Nan, Lin, Neng-Yu, Stefanica, Adrian, Nüchel, Julian, Chen, Chih-Wei, Hsu, Hsiao-Han, Zhu, Honglin, Ding, Xiao, Huang, Jingang, Shen, Lichong, Györfi, Andrea-Hermina, Soare, Alina, Rauber, Simon, Bergmann, Christina, Ramming, Andreas, Plomann, Markus, Eckes, Beate, Schett, Georg, Distler, Jörg H. W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292318/ https://www.ncbi.nlm.nih.gov/pubmed/34285225 http://dx.doi.org/10.1038/s41467-021-24601-y |
Ejemplares similares
-
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis
por: Zehender, Ariella, et al.
Publicado: (2018) -
An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
por: Nüchel, Julian, et al.
Publicado: (2021) -
GRASPing the unconventional secretory machinery to bridge cellular stress signaling to the extracellular proteome
por: Demetriades, Constantinos, et al.
Publicado: (2021) -
The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis
por: Latrasse, David, et al.
Publicado: (2008) -
Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153
por: Li, Yi-Nan, et al.
Publicado: (2022)