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Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60

Human mitochondrial chaperonin mHsp60 is essential for mitochondrial function by assisting folding of mitochondrial proteins. Unlike the double-ring bacterial GroEL, mHsp60 exists as a heptameric ring that is unstable and dissociates to subunits. The structural dynamics has been implicated for a uni...

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Detalles Bibliográficos
Autores principales: Wang, Joseph Che-Yen, Chen, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292379/
https://www.ncbi.nlm.nih.gov/pubmed/34285302
http://dx.doi.org/10.1038/s41598-021-94236-y