Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour

Stimulator of interferon genes (STING) promotes anti-tumour immunity by linking innate and adaptive immunity, but it remains unclear how intratumoural treatment with STING agonists yields anti-tumour effects. Here we demonstrate that intratumoural injection of the STING agonist cGAMP induces strong,...

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Detalles Bibliográficos
Autores principales: Jeong, Seung-hwan, Yang, Myung Jin, Choi, Seunghyeok, Kim, JungMo, Koh, Gou Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292391/
https://www.ncbi.nlm.nih.gov/pubmed/34285232
http://dx.doi.org/10.1038/s41467-021-24603-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292391/
https://www.ncbi.nlm.nih.gov/pubmed/34285232
http://dx.doi.org/10.1038/s41467-021-24603-w

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