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Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour
Stimulator of interferon genes (STING) promotes anti-tumour immunity by linking innate and adaptive immunity, but it remains unclear how intratumoural treatment with STING agonists yields anti-tumour effects. Here we demonstrate that intratumoural injection of the STING agonist cGAMP induces strong,...
Autores principales: | Jeong, Seung-hwan, Yang, Myung Jin, Choi, Seunghyeok, Kim, JungMo, Koh, Gou Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292391/ https://www.ncbi.nlm.nih.gov/pubmed/34285232 http://dx.doi.org/10.1038/s41467-021-24603-w |
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