Altered expression of genes controlling metabolism characterizes the tissue response to immune injury in lupus

To compare lupus pathogenesis in disparate tissues, we analyzed gene expression profiles of human discoid lupus erythematosus (DLE) and lupus nephritis (LN). We found common increases in myeloid cell-defining gene sets and decreases in genes controlling glucose and lipid metabolism in lupus-affected...

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Detalles Bibliográficos
Autores principales: Kingsmore, Kathryn M., Bachali, Prathyusha, Catalina, Michelle D., Daamen, Andrea R., Heuer, Sarah E., Robl, Robert D., Grammer, Amrie C., Lipsky, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292402/
https://www.ncbi.nlm.nih.gov/pubmed/34285256
http://dx.doi.org/10.1038/s41598-021-93034-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292402/
https://www.ncbi.nlm.nih.gov/pubmed/34285256
http://dx.doi.org/10.1038/s41598-021-93034-w

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