TGF-β1-mediated exosomal lnc-MMP2-2 increases blood–brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis

Brain metastases remain a major problem in patients with advanced non-small cell lung cancer (NSCLC). The permeability of the blood–brain barrier (BBB) is highly increased during lung cancer brain metastasis; however, the underlying mechanism remains largely unknown. We previously found that lnc-MMP...

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Detalles Bibliográficos
Autores principales: Wu, Dongming, Deng, Shihua, Li, Li, Liu, Teng, Zhang, Ting, Li, Jing, Yu, Ye, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292445/
https://www.ncbi.nlm.nih.gov/pubmed/34285192
http://dx.doi.org/10.1038/s41419-021-04004-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292445/
https://www.ncbi.nlm.nih.gov/pubmed/34285192
http://dx.doi.org/10.1038/s41419-021-04004-z

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