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Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression
Heterogeneity within a tumour increases its ability to adapt to constantly changing constraints, but adversely affects a patient’s prognosis, therapy response and clinical outcome. Intratumoural heterogeneity results from a combination of extrinsic factors from the tumour microenvironment and intrin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292450/ https://www.ncbi.nlm.nih.gov/pubmed/33824479 http://dx.doi.org/10.1038/s41416-021-01328-7 |