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Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity

The WMI and WLI inbred rats were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain. These were selected using bi-directional selection for immobility in the forced swim test and were then sib-mated for over 38 generations. Despite the low level of genetic diversity...

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Detalles Bibliográficos
Autores principales: de Jong, Tristan V., Kim, Panjun, Guryev, Victor, Mulligan, Megan K., Williams, Robert W., Redei, Eva E., Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292482/
https://www.ncbi.nlm.nih.gov/pubmed/34285244
http://dx.doi.org/10.1038/s41598-021-92993-4