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Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity
The WMI and WLI inbred rats were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain. These were selected using bi-directional selection for immobility in the forced swim test and were then sib-mated for over 38 generations. Despite the low level of genetic diversity...
Autores principales: | de Jong, Tristan V., Kim, Panjun, Guryev, Victor, Mulligan, Megan K., Williams, Robert W., Redei, Eva E., Chen, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292482/ https://www.ncbi.nlm.nih.gov/pubmed/34285244 http://dx.doi.org/10.1038/s41598-021-92993-4 |
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