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Bromodomain-containing protein BRPF1 is a therapeutic target for liver cancer

Epigenetic deregulation plays an essential role in hepatocellular carcinoma (HCC) progression. Bromodomains are epigenetic “readers” of histone acetylation. Recently, bromodomain inhibitors have exhibited promising therapeutic potential for cancer treatment. Using transcriptome sequencing, we identi...

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Detalles Bibliográficos
Autores principales: Cheng, Carol Lai-Hung, Tsang, Felice Hoi-Ching, Wei, Lai, Chen, Mengnuo, Chin, Don Wai-Ching, Shen, Jialing, Law, Cheuk-Ting, Lee, Derek, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin, Wong, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292510/
https://www.ncbi.nlm.nih.gov/pubmed/34285329
http://dx.doi.org/10.1038/s42003-021-02405-6