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Novel self-amplificatory loop between T cells and tenocytes as a driver of chronicity in tendon disease

OBJECTIVES: Increasing evidence suggests that inflammatory mechanisms play a key role in chronic tendon disease. After observing T cell signatures in human tendinopathy, we explored the interaction between T cells and tendon stromal cells or tenocytes to define their functional contribution to tissu...

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Detalles Bibliográficos
Autores principales: Garcia-Melchor, Emma, Cafaro, Giacomo, MacDonald, Lucy, Crowe, Lindsay A N, Sood, Shatakshi, McLean, Michael, Fazzi, Umberto G, McInnes, Iain B, Akbar, Moeed, Millar, Neal L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292554/
https://www.ncbi.nlm.nih.gov/pubmed/33692018
http://dx.doi.org/10.1136/annrheumdis-2020-219335