Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis

OBJECTIVES: To determine how gene expression profiles in osteoarthritis joint tissues relate to patient phenotypes and whether molecular subtypes can be reproducibly captured by a molecular classification algorithm. METHODS: We analysed RNA sequencing data from cartilage and synovium in 113 osteoart...

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Detalles Bibliográficos
Autores principales: Steinberg, Julia, Southam, Lorraine, Fontalis, Andreas, Clark, Matthew J, Jayasuriya, Raveen L, Swift, Diane, Shah, Karan M, Brooks, Roger A, McCaskie, Andrew W, Wilkinson, Jeremy Mark, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Osteoarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292595/
https://www.ncbi.nlm.nih.gov/pubmed/33903094
http://dx.doi.org/10.1136/annrheumdis-2020-219760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292595/
https://www.ncbi.nlm.nih.gov/pubmed/33903094
http://dx.doi.org/10.1136/annrheumdis-2020-219760

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