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Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis
OBJECTIVES: To determine how gene expression profiles in osteoarthritis joint tissues relate to patient phenotypes and whether molecular subtypes can be reproducibly captured by a molecular classification algorithm. METHODS: We analysed RNA sequencing data from cartilage and synovium in 113 osteoart...
Autores principales: | Steinberg, Julia, Southam, Lorraine, Fontalis, Andreas, Clark, Matthew J, Jayasuriya, Raveen L, Swift, Diane, Shah, Karan M, Brooks, Roger A, McCaskie, Andrew W, Wilkinson, Jeremy Mark, Zeggini, Eleftheria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292595/ https://www.ncbi.nlm.nih.gov/pubmed/33903094 http://dx.doi.org/10.1136/annrheumdis-2020-219760 |
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