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Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren’s syndrome-like phenotype in mice

OBJECTIVES: Sjögren’s syndrome (SS) is an autoimmune sialadenitis with unknown aetiology. Although extensive research implicated an abnormal immune response associated with lymphocytes, an initiating event mediated by salivary gland epithelial cell (SGEC) abnormalities causing activation is poorly c...

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Detalles Bibliográficos
Autores principales: Nakamura, Hiroyuki, Tanaka, Tsutomu, Pranzatelli, Thomas, Ji, Youngmi, Yin, Hongen, Perez, Paola, Afione, Sandra A, Jang, Shyh-Ing, Goldsmith, Corrine, Zheng, Chang Yu, Swaim, William D, Warner, Blake M, Hirata, Noriyuki, Noguchi, Masayuki, Atsumi, Tatsuya, Chiorini, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292598/
https://www.ncbi.nlm.nih.gov/pubmed/33658234
http://dx.doi.org/10.1136/annrheumdis-2020-219649