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Lysosome-associated membrane protein 3 misexpression in salivary glands induces a Sjögren’s syndrome-like phenotype in mice
OBJECTIVES: Sjögren’s syndrome (SS) is an autoimmune sialadenitis with unknown aetiology. Although extensive research implicated an abnormal immune response associated with lymphocytes, an initiating event mediated by salivary gland epithelial cell (SGEC) abnormalities causing activation is poorly c...
Autores principales: | Nakamura, Hiroyuki, Tanaka, Tsutomu, Pranzatelli, Thomas, Ji, Youngmi, Yin, Hongen, Perez, Paola, Afione, Sandra A, Jang, Shyh-Ing, Goldsmith, Corrine, Zheng, Chang Yu, Swaim, William D, Warner, Blake M, Hirata, Noriyuki, Noguchi, Masayuki, Atsumi, Tatsuya, Chiorini, John A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292598/ https://www.ncbi.nlm.nih.gov/pubmed/33658234 http://dx.doi.org/10.1136/annrheumdis-2020-219649 |
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