Ubiquitination Destabilizes Protein Sphingosine Kinase 2 to Regulate Glioma Malignancy

Gliomas are the most common and lethal malignant tumor in the central nervous system. The tumor oncogene sphingosine kinase 2 (SphK2) was previously found to be upregulated in glioma tissues and enhance glioma cell epithelial-to-mesenchymal transition through the AKT/β-catenin pathway. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Wang, Hongliang, Zhao, Bing, Bian, Erbao, Zong, Gang, He, Jie, Wang, Yuyang, Ma, Chunchun, Wan, Jinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292629/
https://www.ncbi.nlm.nih.gov/pubmed/34305532
http://dx.doi.org/10.3389/fncel.2021.660354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292629/
https://www.ncbi.nlm.nih.gov/pubmed/34305532
http://dx.doi.org/10.3389/fncel.2021.660354

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