Mechanism of BIP-4 mediated inhibition of InsP(3)Kinase-A

Overexpression of the neuronal InsP(3)kinase-A increases malignancy of different tumor types. Since InsP(3)kinase-A highly selectively binds Ins(1,4,5)P(3), small molecules competing with Ins(1,4,5)P(3) provide a promising approach for the therapeutic targeting of InsP(3)kinase-A. Based on this cons...

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Detalles Bibliográficos
Autores principales: Paraschiakos, Themistoklis, Flat, Wilhelm, Chen, Ya, Kirchmair, Johannes, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292763/
https://www.ncbi.nlm.nih.gov/pubmed/34232294
http://dx.doi.org/10.1042/BSR20211259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292763/
https://www.ncbi.nlm.nih.gov/pubmed/34232294
http://dx.doi.org/10.1042/BSR20211259

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