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Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Although the 5‐year survival rate is high, some patients respond poorly to chemotherapy or have recurrence in locations such as the testis. The blood–testis barrier (BTB) can prevent complete eradication by lim...

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Detalles Bibliográficos
Autores principales: Miller, Siennah R., Jilek, Joseph L., McGrath, Meghan E., Hau, Raymond K., Jennings, Erin Q., Galligan, James J., Wright, Stephen H., Cherrington, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292784/
https://www.ncbi.nlm.nih.gov/pubmed/34288585
http://dx.doi.org/10.1002/prp2.831