In Vivo Induction of Regulatory T Cells Via CTLA‐4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse

Regulatory T cells play a key role in immune tolerance to self‐antigens, thereby preventing autoimmune diseases. However, no drugs targeting Treg cells have been approved for clinical trials yet. Here, a chimeric peptide is generated by conjugation of the cytoplasmic domain of CTLA‐4 (ctCTLA‐4) with...

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Detalles Bibliográficos
Autores principales: Kim, Gil‐Ran, Kim, Won‐Ju, Lim, Sangho, Lee, Hong‐Gyun, Koo, Ja‐Hyun, Nam, Kyung‐Ho, Kim, Sung‐Min, Park, Sung‐Dong, Choi, Je‐Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292875/
https://www.ncbi.nlm.nih.gov/pubmed/34306974
http://dx.doi.org/10.1002/advs.202004973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292875/
https://www.ncbi.nlm.nih.gov/pubmed/34306974
http://dx.doi.org/10.1002/advs.202004973

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