SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

Chromosomal translocation results in development of an Ewing sarcoma breakpoint region 1‐Friend leukemia integration 1 (EWS–FLI1) fusion oncogene in the majority of Ewing sarcoma. The persistent dependence of the tumor for this oncoprotein points to EWS–FLI1 as an ideal drug target. Although EWS–FLI...

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Detalles Bibliográficos
Autores principales: Su, Siyuan, Chen, Jianfeng, Jiang, Yao, Wang, Ying, Vital, Tamara, Zhang, Jiaming, Laggner, Christian, Nguyen, Kong T., Zhu, Zhichuan, Prevatte, Alex W., Barker, Natalie K., Herring, Laura E., Davis, Ian J., Liu, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292909/
https://www.ncbi.nlm.nih.gov/pubmed/34060252
http://dx.doi.org/10.1002/advs.202004846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292909/
https://www.ncbi.nlm.nih.gov/pubmed/34060252
http://dx.doi.org/10.1002/advs.202004846

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