A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression

Forward genetics in the mouse continues to be a useful and unbiased approach to identifying new genes and alleles with previously unappreciated roles in mammalian development and disease. Here, we report a new mouse allele of Cse1l that was recovered from an ENU mutagenesis screen. Embryos homozygou...

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Detalles Bibliográficos
Autores principales: Blizzard, Lauren E., Menke, Chelsea, Patel, Shaili D., Waclaw, Ronald R., Lachke, Salil A., Stottmann, Rolf W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293161/
https://www.ncbi.nlm.nih.gov/pubmed/34287339
http://dx.doi.org/10.3390/jdb9030027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293161/
https://www.ncbi.nlm.nih.gov/pubmed/34287339
http://dx.doi.org/10.3390/jdb9030027

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