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Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells
Sorafenib, an oral multi-tyrosine kinase inhibitor, has been the first-line therapy for the treatment of patients with advanced HCC, providing a survival benefit of only three months in approximately 30% of patients. Cancer stem cells (CSCs) are a rare tumour subpopulation with self-renewal and diff...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293268/ https://www.ncbi.nlm.nih.gov/pubmed/34208001 http://dx.doi.org/10.3390/curroncol28030200 |