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Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis

Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are unclear and may involve sustained activation of renal innate immunity, with resulting renal inflammation and fibrosis. We investigated whether the...

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Detalles Bibliográficos
Autores principales: Albino, Amanda Helen, Zambom, Fernanda Florencia Fregnan, Foresto-Neto, Orestes, Oliveira, Karin Carneiro, Ávila, Victor Ferreira, Arias, Simone Costa Alarcon, Seguro, Antonio Carlos, Malheiros, Denise Maria Avancini Costa, Camara, Niels Olsen Saraiva, Fujihara, Clarice Kazue, Zatz, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293269/
https://www.ncbi.nlm.nih.gov/pubmed/34305624
http://dx.doi.org/10.3389/fphys.2021.606392